Special features: commentary by Sean Hayes, director Lawrence Guterman, producer Chris DeFaria, and production designer James Bissell ; "HBO First Look: Cats & dogs" ; "Teaching a new dog new tricks" storyboard comparisons ; interactive trivia challenge ; theatrical trailer. DVD-ROM PC enhanced features: Fetch the director's alternate ending ; create secret identities for pets ; view production artwork ; download screensavers and wallpaper.

DVD release of the 2001 motion picture.

Director of photogaphy, Julio Macat ; editor, Michael Stevenson ; music, John Debney ; production designer, James Bissell.

Voices: Tobey Maguire, Alec Baldwin, Susan Sarandon, Jon Lovitz, Charlton Heston, Sean Hayes.

Jeff Goldblum, Elizabeth Perkins, Alexander Pollock.

Know to be man's best friends, cats and dogs have engaged in a fierce and merciless battle. Now, Mr. Tinkles, a ruthless cat, is plotting intensively to achieve nothing less than world domination. His main target is Professor Brody. The professor is working on a medication that will rid people of their dog hair allergies. Mr. Tinkles strives to get to the substance and have it analyzed. He then means to have it altered so that all humans of the world become allergic to any kind of dog. Cats would rule and dogs would then be exterminated. Lou is the Brody family's new puppy. He has never heard of dog agents and the major protective mission they fulfill towards the unsuspecting Brody family. Lou, along with Butch and a few other dog agents from the neighborhood desperately tries to hinder Mr. Tinkles in his sinister plans to take over the world.

MPAA rating: PG; for animal action and humor.

DVD ; region 1 ; widescreen (matted, enhanced) presentation ; Dolby Digital 5.1 surround, dual-layer.

In English or dubbed French dialogue, with optional English, French or Spanish subtitles.

Closed-captioned.